The discovery of diet pills which made spending hours in a gym as well as adhering to a demanding dieting program redundant to a specific extent, created a rage in the marketplace. They ended up to be a blessing in disguise for the whole pharmaceutical industry, which is today’s earning of significant revenues with the sale of these pills. It has been estimated that greater than 20 million of Americans consume diet plan drugs each year.
The History of Diet Pills
It had been during the ten years of 1950s when science as well as medicine were producing striking accomplishments that these capsules had been first prescribed by the doctors for the individuals. The doctors prescribed amphetamines, a drug applied to the World War II to maintain soldiers alert and productive, for weight loss purpose. Among the negative effects of amphetamines was appetite suppression that led doctors in prescribing them as weight loss supplements. Before long many weight loss patients went through amphetamines led substance abuse problems as well as its prescription was inhibited.
It was in 1970s when wellness consciousness sprung up to the pinnacle of its as well as fitness became a global craze. Weight reduction became the name of the game and also the pharmaceutical industry saw an unexpected boom in the demand learn more here for them. The first such drugs in this era were essentially amphetamines derivatives, normally known as “speed”. Afterwards, an assortment of weight loss capsules flooded the market.
Food as well as Drug Administration (FDA) approved the drug fenfluramine (Pondimin) in as early as 1973, that was followed by dexfenfluramine (Redux) in 1996. Then came the diet drug Phentermine, a sympathomimetic appetite suppressant, that had been approved by the FDA in 1997. Many medical professionals prescribed Phentermine in conjunction with fenfluramine. The combined prescription of both the prescriptions was aptly named fen phen.
The era of fen-phen soon declined with reports of heart valve disease resulting from the combined utilization of each prescription drugs started to surface. The makers withdrew dexfenfluramine as well as fenfluramine from the market, thereby ending the rule of fen-phen.
The most popular weight reduction medicines that are recommended in the US are sympathomimetic appetite suppressants like Phentermine. These drugs affect the neurotransmitters in a way that brings about a loss in appetite.
Other weightloss pills that received FDA approval are Orlistat (Xenical) and Sibutramine (Meridia), which received approval in 1999 and 2001 respectively. While Orlistat is a lipase inhibitor which prevents the absorption of dietary fats to the entire body, Sinutramine acts on mental through serotonin, norepinephrine as well as dopamine reuptake inhibition.