Testosterone is predominantly produced by the testes in men. Small quantities are produced by the ovaries in females. The adrenal glands also make very small quantities in both sexes. Testosterone plays an important part in sexual functioning. Besides helping in the production of sperms, this steroid hormone additionally improves libido, boosts energy, helps make white blood cells and helps to protect against osteoporosis. Testosterone is an androgen as well as an anabolic steroid.

The blood levels of testosterone vary over a broad selection. Testosterone levels gradually begin declining throughout the third or first fourth decade of life in a constant rate. As a result, older males have significantly lower levels as compared to the younger counterparts of theirs. Testosterone levels may in addition be low due to a number of diseases. The cutoff number is 250 ng/dL, amounts beneath these’re considered low.

What’s the connection between testosterone as well as heart disease?

Lower testosterone levels have been associated with increased risk of death and development from cardiovascular disease. In a recent study by Associates and Laughlin, males with low levels and in probably the lowest quartile were 40 % more likely to die early, especially from cardiovascular diseases. These findings were unaffected by age range, other risk factors and lipid levels. The study needed 794 males aged 50-91 years, who were monitored for twenty years. The study was posted in 2008 in the Journal of Clinical Metabolism and Endocrinology.

In 2007, outcomes of the European Prospective Investigation into Cancer in Norfolk Study have been written and published in Circulation. In this particular research, Khaw and associates monitored 11,000 patients aged 40-79 for their testosterone levels and death. They found out that the latter were inversely related – low testosterone levels correlated with a higher rate of death from cardiovascular disease, various other factors and cancer.

In an additional study, shores & Colleagues, discovered that low testosterone levels happened to be associated with an increased risk for mortality in male veterans. The male population was more than 40 years of age and did not have prostate cancer. The study was done in Seattle and released in the Archives of Internal Medicine in 2006.

How does low boost testosterone (clicking here) cause cardiovascular disease?

The mechanism by which decreased testosterone causes cardiovascular disease just isn’t clear, but you’ll find a number of postulated mechanisms. Individuals with low testosterone levels generally have more visceral obesity. Visceral obesity is responsible for the apple shaped body (as as compared to the pear shaped body, in that the fat is predominantly deposited in the hips as well as buttocks). More generally, this’s called the’ pot belly’ or’ beer belly’. The visceral fat is loaded between the inner organs in the peritoneal cavity (abdominal cavity). In comparison the subcutaneous fat is found under the skin and the intramuscular extra fat in the skeletal muscle. Visceral fat is much more metabolically active and synthesizes more center unhealthy fatty acids, triglycerides, and also adipokines than nonvisceral fat. Low testosterone also is associated with the enhancement of metabolic syndrome and diabetes. In an investigation published in 2007, men in probably the lowest amounts of testosterone were 4 times more likely to develop diabetes in comparison with men with the highest levels. This data from the Third National Nutrition and Health Examination Survey, was published by Selvin and Group in Diabetes Care. Patients with low testosterone levels have increased levels of insulin as well as triglycerides, both damaging to the cardiovascular system.

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